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Burmann, Björn M. ; Rösch, Paul:
The role of E. coli Nus-factors in transcription regulation and transcription: translation coupling.
In: Transcription.
Bd. 2
(2011)
Heft 3
.
- S. 130-134.
ISSN 2154-1264
DOI: https://doi.org/10.4161/trns.2.3.15671
Abstract
Bacterial transcription mediated by RNA polymerase (RNAP) is a highly regulated process, and RNAP action is modulated during the different phases, initiation, elongation, and termination by proteins such as the Escherichia coli Nus transcription-factors. Here we discuss the structural interplay and the mechanistic role of the Nus-factors that are directly involved in processive elongation, transcription:translation coupling and termination as well as the varying effects of these proteins on transcription under the influence of additional signals.