Photobiologically Directed Assembly of Gold Nanoparticles

Title data

Dietler, Julia ; Liang, Chen ; Frank, Saskia ; Müller, Ann-Kathrin ; Greiner, Andreas ; Möglich, Andreas:
Photobiologically Directed Assembly of Gold Nanoparticles.
In: Advanced Biology. Vol. 5 (2021) Issue 5 . - 2000179.
ISSN 2701-0198
DOI: https://doi.org/10.1002/adbi.202000179

Project information

Abstract in another language

In nature, photoreceptor proteins undergo molecular responses to light, that exhibit supreme fidelity in time and space and generally occur under mild reaction conditions. To unlock these traits for material science, the light-induced homodimerization of light-oxygen-voltage (LOV) photoreceptors is leveraged to control the assembly of gold nanoparticles. Conjugated to genetically encodable LOV proteins, the nanoparticles are monodispersed in darkness but rapidly assemble into large aggregates upon blue-light exposure. The work establishes a new modality for reaction control in macromolecular chemistry and thus augurs enhanced precision in space and time in diverse applications of gold nanoparticles.