Cationic ring-opening polymerization of protected oxazolidine imines resulting in gradient copolymers of poly(2-oxazoline) and poly(urea)

Title data

Leiske, Meike N. ; Hartlieb, Matthias ; Sobotta, Fabian H. ; Paulus, Renzo M. ; Görls, Helmar ; Bellstedt, Peter ; Schubert, Ulrich S.:
Cationic ring-opening polymerization of protected oxazolidine imines resulting in gradient copolymers of poly(2-oxazoline) and poly(urea).
In: Polymer Chemistry. Vol. 7 (2016) Issue 30 . - pp. 4924-4936.
ISSN 1759-9954
DOI: https://doi.org/10.1039/C6PY00785F

Official URL:

Abstract in another language

Poly(urea)s are a polymer class widely used in industry. Their utilization in biomedical applications is already described, however, the use of controlled polymerization methods instead of polycondensation approaches would allow a better control over the degree of polymerization and the dispersity of the resulting polymers, improving their suitability for this particular field of application. Cationic ring-opening polymerization (CROP) as a chain growth polymerization enables those requirements and, additionally, allows the copolymerization with 2-oxazolines, which are generally known for their biocompatibility. In this report, a Boc protected oxazolidine imine monomer is synthesized and polymerized in a homopolymerization, as well as in a copolymerization with 2-ethyl-2-oxazoline (EtOx) via CROP. The synthesized polymers were analyzed regarding their chemical and physical properties, using NMR, GC, MALDI-MS, SEC, TGA and DSC. Copolymerization kinetics revealed the formation of quasi-block copolymers, able to self-assemble in aqueous solution as indicated by DLS.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Institutions of the University:	Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Junior Professor Sustainable and Functional Polymer Systems > Junior Professor Sustainable and Functional Polymer Systems - Juniorprof. Dr. Meike Leiske Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Junior Professor Sustainable and Functional Polymer Systems
Result of work at the UBT:	No
DDC Subjects:	500 Science > 540 Chemistry
Date Deposited:	18 Jan 2023 14:40
Last Modified:	13 Mar 2023 08:44
URI:	https://eref.uni-bayreuth.de/id/eprint/73440