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Poly(2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications : A review

Title data

Leiske, Meike N.:
Poly(2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications : A review.
In: European Polymer Journal. Vol. 185 (2023) . - 111832.
ISSN 1873-1945
DOI: https://doi.org/10.1016/j.eurpolymj.2023.111832

Official URL: Volltext

Abstract in another language

Poly(2-oxazoline)s (POx) are a unique class of polymers with an enormous potential for the preparation of functional materials. Their synthesis via the cationic ring-opening polymerisation (CROP) of 2-oxazolines enables the design of tailored polymers with reactive sites at their α- or ω-end (telechelic POx), or in the side chain. Due to their biocompatibility and low-fouling properties, hydrophilic POx have shown promise as novel stealth-polymers for applications in the biomedical area. In this context, the development of defined high molar mass POx to reduce renal clearance and improve blood circulation times beyond linear polymers has drawn attention. In this contribution, different strategies for the design of star-shaped POx will be summarised. The CROP of 2-oxazolines is presented as a manifold tool to obtain cross-linked or branched star-like materials. In addition, strategies which combine CROP with other controlled polymerisation techniques will be discussed. Star-shaped POx are showcased a versatile platform to create high molar mass POx in a controlled manner and tune the properties of the resulting polymers.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Junior Professor Sustainable and Functional Polymer Systems > Junior Professor Sustainable and Functional Polymer Systems - Juniorprof. Dr. Meike Leiske
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Junior Professor Sustainable and Functional Polymer Systems
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 18 Jan 2023 14:46
Last Modified: 13 Feb 2024 08:40
URI: https://eref.uni-bayreuth.de/id/eprint/73454