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Spider Silk for Tissue Engineering Applications

Title data

Salehi, Sahar ; Koeck, Kim ; Scheibel, Thomas:
Spider Silk for Tissue Engineering Applications.
In: Molecules. Vol. 25 (2020) Issue 3 . - 737.
ISSN 1420-3049

Abstract in another language

Due to its properties, such as biodegradability, low density, excellent biocompatibility and unique mechanics, spider silk has been used as a natural biomaterial for a myriad of applications. First clinical applications of spider silk as suture material go back to the 18th century. Nowadays, since natural production using spiders is limited due to problems with farming spiders, recombinant production of spider silk proteins seems to be the best way to produce material in sufficient quantities. The availability of recombinantly produced spider silk proteins, as well as their good processability has opened the path towards modern biomedical applications. Here, we highlight the research on spider silk-based materials in the field of tissue engineering and summarize various two-dimensional (2D) and three-dimensional (3D) scaffolds made of spider silk. Finally, different applications of spider silk-based materials are reviewed in the field of tissue engineering in vitro and in vivo.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: tissue engineering; biofabrication; hydrogels; coatings; fibers; recombinant spider silk proteins
Institutions of the University: Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 09 Mar 2023 12:51
Last Modified: 09 Mar 2023 12:51