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Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing

Titelangaben

Sadeghian, Ramin Banan ; Han, Jiuhui ; Ribas, João ; Nasajpour, Amir ; Duchamp, Margaux ; Mousavi Shaegh, Seyed Ali ; Ostrovidov, Serge ; Salehi, Sahar ; Chen, Mingwei ; Khademhosseini, Ali:
Application of nanoporous gold in planar and mesh forms in electrochemical superoxide biosensing.
In: 2016 IEEE 16th International Conference on Nanotechnology (IEEE-NANO). - Piscataway, NJ : IEEE , 2016 . - S. 19-21
ISBN 978-1-5090-1493-4
DOI: https://doi.org/10.1109/NANO.2016.7751411

Abstract

We employed the large surface-to-volume ratio of nanoporous gold (NPG) to build a set of highly sensitive superoxide electrochemical biosensors. Once functionalized with cytochrome-c (cyt-c) the NPG-based electrodes displayed a superoxide sensitivity of 0.24 nA nM -1 and a low-level of detection of 5 nM towards superoxide. The planar electrodes were then interfaced with HUVEC cells and were able to detect the release of extracellular superoxide upon stimulation with an endogenous superoxide producer. In addition, we studied the superoxide sensing performance of a three-dimensional (3D) macroporous mesh of gold decorated with NPG as a potential ultrasensitive superoxide biosensor.

Weitere Angaben

Publikationsform: Aufsatz in einem Buch
Begutachteter Beitrag: Ja
Institutionen der Universität: Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Biomaterialien
Titel an der UBT entstanden: Nein
Themengebiete aus DDC: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften
Eingestellt am: 10 Mär 2023 08:41
Letzte Änderung: 10 Mär 2023 08:41
URI: https://eref.uni-bayreuth.de/id/eprint/74177