at Google ScholarTitle data
Ahadian, Samad ; Sadeghian, Ramin Banan ; Salehi, Sahar ; Ostrovidov, Serge ; Bae, Hojae ; Ramalingam, Murugan ; Khademhosseini, Ali:
Bioconjugated Hydrogels for Tissue Engineering and Regenerative Medicine.
In: Bioconjugate Chemistry.
Vol. 26
(2015)
Issue 10
.
- pp. 1984-2001.
ISSN 1520-4812
DOI: https://doi.org/10.1021/acs.bioconjchem.5b00360
Abstract in another language
Hydrogels are hydrophilic polymer networks with high water content, which have played an important role as scaffolds for cells, as carriers for various biomolecules (e.g., drugs, genes, and soluble factors), and as injectable biomaterials in tissue engineering (TE) and regenerative medicine. Bioconjugation is an approach for improving the performance of hydrogels using cell-responsive components, such as proteins and peptides, which have high affinity to regulate cellular behaviors and tissue morphogenesis. However, the current knowledge on the role of those bioconjugated moieties in controlling cellular functions and tissue morphogenesis and bioconjugation methods are limited in the context of TE and organogenesis. Moreover, micro- and nanofabrication techniques have been used to manipulate bioconjugated hydrogels for regulating cell behaviors and function. This Review therefore describes synthesis, characteristics, and manipulation of various bioconjugated hydrogels and their potential in TE applications with special emphasis on preclinical/clinical translation.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Engineering Science > Chair Biomaterials |
| Result of work at the UBT: | No |
| DDC Subjects: | 600 Technology, medicine, applied sciences > 610 Medicine and health 600 Technology, medicine, applied sciences > 620 Engineering |
| Date Deposited: | 10 Mar 2023 11:00 |
| Last Modified: | 10 Mar 2023 11:00 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/74184 |