at Google ScholarTitle data
Bocklitz, Thomas ; Crecelius, Anna C. ; Matthäus, Christian ; Tarcea, Nicolae ; von Eggeling, Ferdinand ; Schmitt, Michael ; Schubert, Ulrich S. ; Popp, Jürgen:
Deeper understanding of biological tissue : Quantitative correlation of MALDI-TOF and Raman imaging.
In: Analytical Chemistry.
Vol. 85
(2013)
Issue 22
.
- pp. 10829-10834.
ISSN 1520-6882
DOI: https://doi.org/10.1021/ac402175c
Abstract in another language
In order to achieve a comprehensive description of biological tissue, spectral information about proteins, lipids, nucleic acids, and other biochemical components need to be obtained concurrently. Different analytical techniques may be combined to record complementary information of the same sample. Established techniques, which can be utilized to elucidate the biochemistry of tissue samples are, for instance, MALDI-TOF-MS and Raman microscopic imaging. With this contribution, we combine these two techniques for the first time. The combination of both techniques allows the utilization and interpretation of complementary information (i.e., the information about the protein composition derived from the Raman spectra with data of the lipids analyzed by the MALDI-TOF measurements). Furthermore, we demonstrate how spectral information from MALDI-TOF experiments can be utilized to interpret Raman spectra.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Computer Science > Lehrstuhl Künstliche Intelligenz in der Mikroskopie und Spektroskopie > Lehrstuhl Künstliche Intelligenz in der Mikroskopie und Spektroskopie - Univ.-Prof. Dr. Thomas Wilhelm Bocklitz |
| Result of work at the UBT: | No |
| DDC Subjects: | 500 Science > 530 Physics |
| Date Deposited: | 19 May 2023 10:19 |
| Last Modified: | 19 May 2023 10:19 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/76291 |