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Hydrogel Micropillars with Integrin Selective Peptidomimetic Functionalized Nanopatterned Tops : A New Tool for the Measurement of Cell Traction Forces Transmitted through αᵥβ₃‐or α₅β₁‐Integrins

Title data

Rahmouni, Sabri ; Lindner, Aaron ; Rechenmacher, Florian ; Neubauer, Stefanie ; Sobahi, Tariq Rashad Ali ; Kessler, Horst ; Cavalcanti-Adam, Elisabetta Ada ; Spatz, Joachim Pius:
Hydrogel Micropillars with Integrin Selective Peptidomimetic Functionalized Nanopatterned Tops : A New Tool for the Measurement of Cell Traction Forces Transmitted through αᵥβ₃‐or α₅β₁‐Integrins.
In: Advanced Materials. Vol. 25 (2013) Issue 41 . - pp. 5869-5874.
ISSN 1521-4095
DOI: https://doi.org/10.1002/adma.201301338

Abstract in another language

Poly(ethylene glycol) micropillars with gold nanopatterns on top are functionalized with two integrin selective ligands. This platform is a powerful new tool to determine the specific contribution of traction forces involved in cell adhesion mediated by α5 β1- and αvβ3- integrins. Cells adherent via α5 β1-integrins have a tendency to exert higher maximum forces than cells adhering via αvβ3-integrins.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Engineering Science > Chair Cellular Biomechanics > Chair Cellular Biomechanics - Univ.-Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam
Result of work at the UBT: No
DDC Subjects: 600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 12 Jun 2023 12:46
Last Modified: 12 Jun 2023 12:46
URI: https://eref.uni-bayreuth.de/id/eprint/81167