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Surface Patterning for the Control of Receptor Clustering and Molecular Forces of Integrin-Mediated Adhesions

Title data

Pennarola, Federica ; Cavalcanti-Adam, Elisabetta Ada:
Surface Patterning for the Control of Receptor Clustering and Molecular Forces of Integrin-Mediated Adhesions.
In: Vicente-Manzanares, Miguel (ed.): The Integrin Interactome : Methods and Protocols. - New York : Springer US , 2021 . - pp. 183-195
ISBN 978-1-07-160962-0
DOI: https://doi.org/10.1007/978-1-0716-0962-0_11

Abstract in another language

Surface nanopatterning allows for the creation of spatially controlled binding sites for extracellular matrix ligands and the modulation of receptor binding sites. Here we describe the preparation of gold nanopatterned substrates using diblock micellar nanolithography to immobilize integrin ligands at defined spacing and combined with molecular tension sensors to measure molecular forces as function of integrin lateral clustering.

Further data

Item Type: Article in a book
Refereed: Yes
Keywords: Block copolymer micellar nanolithography; Nanopatterns; Integrins; Focal adhesions; Molecular tension sensors; Integrative tension sensors
Institutions of the University: Faculties > Faculty of Engineering Science > Chair Cellular Biomechanics > Chair Cellular Biomechanics - Univ.-Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam
Result of work at the UBT: No
DDC Subjects: 600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 07 Jun 2023 06:36
Last Modified: 07 Jun 2023 06:36
URI: https://eref.uni-bayreuth.de/id/eprint/81223