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Efficacy of Fasting in Type 1 and Type 2 Diabetes Mellitus : A Narrative Review

Title data

Herz, Daniel ; Haupt, Sandra ; Zimmer, Rebecca T. ; Wachsmuth, Nadine ; Schierbauer, Janis ; Zimmermann, Paul ; Voit, Thomas ; Thurm, Ulrike ; Khoramipour, Kayvan ; Rilstone, Sian ; Moser, Othmar:
Efficacy of Fasting in Type 1 and Type 2 Diabetes Mellitus : A Narrative Review.
In: Nutrients. Vol. 15 (2023) Issue 16 . - 3525.
ISSN 2072-6643
DOI: https://doi.org/10.3390/nu15163525

Abstract in another language

Over the last decade, studies suggested that dietary behavior modification, including fasting, can improve metabolic and cardiovascular markers as well as body composition. Given the increasing prevalence of people with type 1 (T1DM) and type 2 diabetes mellitus (T2DM) and the increasing obesity (also in combination with diabetes), nutritional therapies are gaining importance, besides pharmaceutical interventions. Fasting has demonstrated beneficial effects for both healthy individuals and those with metabolic diseases, leading to increased research interest in its impact on glycemia and associated short- and long-term complications. Therefore, this review aimed to investigate whether fasting can be used safely and effectively in addition to medications to support the therapy in T1DM and T2DM. A literature search on fasting and its interaction with diabetes was conducted via PubMed in September 2022. Fasting has the potential to minimize the risk of hypoglycemia in T1DM, lower glycaemic variability, and improve fat metabolism in T1DM and T2DM. It also increases insulin sensitivity, reduces endogenous glucose production in diabetes, lowers body weight, and improves body composition. To conclude, fasting is efficient for therapy management for both people with T1DM and T2DM and can be safely performed, when necessary, with the support of health care professionals.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: diabetes mellitus; fasting interventions; intermittent fasting; time-restricted fasting; periodic fasting; Ramadan fasting
Institutions of the University: Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology > Chair Exercise Physiology - Univ.-Prof. Dr. Othmar Moser
Faculties
Faculties > Faculty of Cultural Studies
Faculties > Faculty of Cultural Studies > Department of Sport Science
Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
Date Deposited: 23 Oct 2023 08:16
Last Modified: 24 Oct 2023 08:36
URI: https://eref.uni-bayreuth.de/id/eprint/87321