Literature by the same author
plus at Google Scholar

Bibliografische Daten exportieren
 

Manganese-catalyzed Dehydrogenation of Amido Alcohols with Liberation of Hydrogen for the Synthesis of Oxazoles

Title data

Leinert, Max ; Irrgang, Torsten ; Kempe, Rhett:
Manganese-catalyzed Dehydrogenation of Amido Alcohols with Liberation of Hydrogen for the Synthesis of Oxazoles.
In: ChemCatChem. Vol. 15 (2023) Issue 22 . - e202301042.
ISSN 1867-3899
DOI: https://doi.org/10.1002/cctc.202301042

Official URL: Volltext

Project information

Project financing: Deutsche Forschungsgemeinschaft

Abstract in another language

Abstract Syntheses of important classes of (heterocyclic) compounds, the sustainable generation of hydrogen, and the use of abundantly available metals are highly desirable. We introduce here a catalytic oxazole synthesis. Our reaction is a regio selective, one-pot reaction and starts from esters and amino alcohols. Both are abundantly and diversely available and inexpensive starting materials. Hydrogen is liberated during the reaction and a molecular earth-abundant metal catalyst, a Mn(I) compound, mediates the reaction most effectively - and more efficiently than Ir and Ru catalysts. None of the oxazole derivatives synthesized, except the screening substrate and an active ingredient of a drug (an application), have been reported in literature yet.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: amino alcohols; dehydrogenation; esters; manganese; oxazoles
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Inorganic Chemistry II > Chair Inorganic Chemistry II - Univ.-Prof. Dr. Rhett Kempe
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Inorganic Chemistry II
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 16 Dec 2023 22:01
Last Modified: 18 Dec 2023 07:27
URI: https://eref.uni-bayreuth.de/id/eprint/88069