Title data
Engeroff, Tobias ; Groneberg, David A. ; Wilke, Jan:
After Dinner Rest a While, After Supper Walk a Mile? A Systematic Review with Meta-analysis on the Acute Postprandial Glycemic Response to Exercise Before and After Meal Ingestion in Healthy Subjects and Patients with Impaired Glucose Tolerance.
In: Sports Medicine.
Vol. 53
(2023)
Issue 4
.
- pp. 849-869.
ISSN 1179-2035
DOI: https://doi.org/10.1007/s40279-022-01808-7
Abstract in another language
BACKGROUND
The most effective way to cope with high blood sugar spikes is to engage in physical activity in temporal proximity to food intake. However, so far, it is unclear as to whether there is an optimal time for physical activity around food intake.
OBJECTIVES
We aimed to identify the impact of pre- and post-meal exercise on postprandial glucose excursions in humans with and without type 2 diabetes mellitus.
METHODS
We conducted a systematic review with meta-analysis, PROSPERO registration number: CRD42022324070. We screened MEDLINE/PubMed, Cochrane/CINAHL/EMBASE, and Web of Knowledge until 1 May, 2022. We used the risk of bias rating with the crossover extension of the Cochrane risk of bias assessment tool II. Standardized mean differences (SMDs, Hedges' g) with 95% confidence intervals (CIs) were calculated as pooled effect estimates of a random-effects meta-analysis. Eligibility criteria included three-armed randomized controlled trials comparing the acute effects of pre- and post-meal exercise to a no-exercise control in humans.
RESULTS
Eight randomized controlled trials (crossover trials, high risk of bias) with 30 interventions in 116 participants (47 diagnosed with type 2 diabetes, 69 without type 2 diabetes) were eligible. Exercise after meal ingestion (real food or meal replacement drinks) led to a reduction in postprandial glucose excursions compared with exercise before eating (15 effect sizes; SMD = 0.47 [95% CI 0.23, 0.70]) and an inactive control condition (15 effect sizes; SMD = 0.55 [95% CI 0.34, 0.75]. Pre-meal exercise did not lead to significantly lower postprandial glucose compared to an inactive control (15 effect sizes; SMD = - 0.13 [95% CI - 0.42, 0.17]). The time between meal and exercise (estimate = - 0.0151; standard error = 0.00473; Z = - 3.19; p = 0.001; 95% CI - 0.024, - 0.006) had a moderating influence on postprandial glucose excursions.
CONCLUSIONS
Exercise, i.e., walking, has a greater acute beneficial impact on postprandial hyperglycemia when undertaken as soon as possible after a meal rather than after a longer interval or before eating.
CLINICAL TRIAL REGISTRATION
The review was pre-registered in the PROSPERO database (CRD42022324070). The date of submission was 07.04.2022, with the registration on 08.05.2022.
Further data
Item Type: | Article in a journal |
---|---|
Refereed: | Yes |
Institutions of the University: | Faculties > Faculty of Cultural Studies Faculties Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Sport Science I - Neuromotorik und Bewegung > Chair Sport Science I - Neuromotorik und Bewegung - Univ.-Prof. Dr. Dr. Jan Wilke |
Result of work at the UBT: | No |
DDC Subjects: | 600 Technology, medicine, applied sciences > 610 Medicine and health |
Date Deposited: | 12 Apr 2024 12:35 |
Last Modified: | 02 May 2024 06:40 |
URI: | https://eref.uni-bayreuth.de/id/eprint/89199 |