bei Google ScholarTitelangaben
Cai, Bao-Gui ; Li, Qian ; Empel, Claire ; Li, Lei ; Koenigs, Rene M. ; Xuan, Jun:
Dark and Light Reactions of Carbenes : Merging Carbene Transfer Reactions with N-Heterocyclic Carbene Catalysis for the Synthesis of Hydroxamic Acid Esters.
In: ACS Catalysis.
Bd. 12
(2022)
.
- S. 11129-11136.
ISSN 2155-5435
DOI: https://doi.org/10.1021/acscatal.2c02875
Abstract
Herein, we report visible light and N-heterocyclic carbene (NHC) jointly promoted multicomponent carbene transfer reactions. Under the optimized reaction conditions, two kinds of important hydroxamic acid esters were obtained in good yields depending on the reaction media used. The key to this success was driven by the blue light-promoted generation of free carbene species and the fast in situ formation of hydroxamic acid under NHC-catalyzed conditions. The mild reaction conditions, excellent functional group tolerance, useful synthetic transformations, and successful modification of natural products and drug molecules proved the utility and practicality of this method.
Weitere Angaben
| Publikationsform: | Artikel in einer Zeitschrift |
|---|---|
| Begutachteter Beitrag: | Ja |
| Keywords: | carbene transfer reactions; carbene catalysis; photochemistry; diazoalkane; hydroxamic acid; computational studies |
| Institutionen der Universität: | Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie |
| Titel an der UBT entstanden: | Nein |
| Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Eingestellt am: | 31 Mär 2025 11:44 |
| Letzte Änderung: | 31 Mär 2025 11:44 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/93078 |