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Continuous-flow photochemical carbene transfer reactions

Title data

Empel, Claire ; Koenigs, Rene M.:
Continuous-flow photochemical carbene transfer reactions.
In: Journal of Flow Chemistry. Vol. 10 (2020) . - pp. 157-160.
ISSN 2063-0212
DOI: https://doi.org/10.1007/s41981-019-00054-9

Abstract in another language

Photochemistry constitutes an important tool to conduct environmentally benign and efficient transformations in organic synthesis. Conventional batch transformations are limited in productivity and scale due to Beer’s law, which can be easily overcome using flow chemistry approaches. Herein, we report on the continuous-flow photolysis of aryl diazoacetates using a glass microreactor and blue LEDs. Following this methodology, we were able to demonstrate the application of continuous-flow chemistry in photochemical cyclopropanation and rearrangement reactions and demonstrate the scalability of photochemical carbene transfer reactions.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry - Univ.-Prof. Dr. René M. Koenigs
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry
Result of work at the UBT: No
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 02 Apr 2025 09:22
Last Modified: 07 Oct 2025 11:03
URI: https://eref.uni-bayreuth.de/id/eprint/93149