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Hock, Katharina J. ; Koenigs, Rene M.:
The Generation of Diazo Compounds in Continuous‐Flow.
In: Chemistry : a European Journal.
Bd. 24
(2018)
.
- S. 10571-10583.
ISSN 1521-3765
DOI: https://doi.org/10.1002/chem.201800136
Abstract
Toxic, cancerogenic and explosive—these attributes are typically associated with diazo compounds. Nonetheless, diazo compounds are nowadays a highly demanded class of reagents for organic synthesis, yet the concerns with regards to safe and scalable transformations of these compounds are still exceptionally high. Lately, the research area of the continuous-flow synthesis of diazo compounds attracted significant interest and a whole variety of protocols for their “on-demand” preparation have been realized to date. This concept article focuses on the recent developments using continuous-flow technologies to access diazo compounds; thus minimizing risks and hazards when working with this particular class of compounds. In this article we discuss these concepts and highlight different pre-requisites to access and to perform downstream functionalization reaction.
Weitere Angaben
| Publikationsform: | Artikel in einer Zeitschrift |
|---|---|
| Begutachteter Beitrag: | Ja |
| Institutionen der Universität: | Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie |
| Titel an der UBT entstanden: | Nein |
| Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Eingestellt am: | 02 Apr 2025 13:09 |
| Letzte Änderung: | 02 Apr 2025 13:09 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/93183 |