Titelangaben
Tran, U. P. N. ; Hock, K. J. ; Gordon, C. P. ; Koenigs, Rene M. ; Nguyen, T. V.:
Efficient phosphine-mediated formal C(sp³)–C(sp³) coupling reactions of alkyl halides in batch and flow.
In: Chemical Communications.
Bd. 53
(2017)
.
- S. 4950-4953.
ISSN 1364-548X
DOI: https://doi.org/10.1039/C7CC02033C
Abstract
The construction of C(sp3)–C(sp3) bond is an essential chemical transformation in synthetic chemistry due to its abundance in organic scaffolds. Here we demonstrate a valuable adaptation of the Wittig-type chemical procedure to efficiently facilitate C(sp3)–C(sp3) bond formation utilizing a range of alkyl building blocks. Additionally the method is amenable with flow synthesis to afford coupled products in good to excellent yields without laborious purification process.
Weitere Angaben
Publikationsform: | Artikel in einer Zeitschrift |
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Begutachteter Beitrag: | Ja |
Institutionen der Universität: | Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie |
Titel an der UBT entstanden: | Nein |
Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
Eingestellt am: | 03 Apr 2025 07:18 |
Letzte Änderung: | 03 Apr 2025 07:18 |
URI: | https://eref.uni-bayreuth.de/id/eprint/93193 |