Electrochemical C-H functionalization reaction of N-heterocycles with alkyl iodides

Titelangaben

Hussain, Yaseen ; Sankar, Ganga ; Rueping, Magnus ; Koenigs, Rene M.:
Electrochemical C-H functionalization reaction of N-heterocycles with alkyl iodides.
In: Chemical Communications. (2025) .
ISSN 1364-548X
DOI: https://doi.org/10.1039/D5CC01836F

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Abstract

Herein we report on an electrochemical protocol for the C–H alkylation of N-heterocycles with easily accessible alkyl halides. A wide range of azauracil derivatives including bioactive terthred azauracil, pyrazinone and quinoxalinone were well accomodated and delivered the alkylated products in good to excellent yield.