Centriole disengagement : What are the relative contributions of Cohesin versus Pericentrin inactivation?

Title data

Kahlen, Philip:
Centriole disengagement : What are the relative contributions of Cohesin versus Pericentrin inactivation?
Bayreuth , 2025 . - 130 p.
( Doctoral thesis, 2024 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)
DOI: https://doi.org/10.15495/EPub_UBT_00008504

Official URL:

Abstract in another language

Centriole disengagement is defined as the spatial separation of centrioles during late mitosis and is thought to act as a licensing step for their duplication in the following cell cycle. This work is focused on the relative contribution of proteolytical inactivation of centrosomal Cohesin and Pericentrin to centriole disengagement.

Abstract in another language

Die Entkopplung der Zentriolen ist definiert als deren räumliche Trennung in später Mitose und dient als Lizenzierungsschritt für die Duplikation im folgenden Zellzyklus. In der vorliegenden Arbeit wird untersucht, wie und in welchen Anteilen die proteolytische Inaktivierung von Kohäsin und Perizentrin zur Entkopplung der Zentriolen beitragen.

Further data

Item Type:	Doctoral thesis
Keywords:	Centrosomes; Centriole disengagement; Cohesin; Pericentrin; Mitosis
Institutions of the University:	Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics > Chair Genetics - Univ.-Prof. Dr. Olaf Stemmann Graduate Schools > University of Bayreuth Graduate School Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics Graduate Schools
Result of work at the UBT:	Yes
DDC Subjects:	500 Science
Date Deposited:	28 Jun 2025 21:00
Last Modified:	28 Jun 2025 21:00
URI:	https://eref.uni-bayreuth.de/id/eprint/94016