Polymer/Bacteria Composite Nanofiber Nonwovens by Electrospinning of Living Bacteria Protected by Hydrogel Microparticles

Titelangaben

Gensheimer, Marco ; Brandis-Heep, Astrid ; Agarwal, Seema ; Thauer, Rudolf K. ; Greiner, Andreas:
Polymer/Bacteria Composite Nanofiber Nonwovens by Electrospinning of Living Bacteria Protected by Hydrogel Microparticles.
In: Macromolecular Bioscience. Bd. 11 (2011) Heft 3 . - S. 333-337.
ISSN 1616-5195
DOI: https://doi.org/10.1002/mabi.201000310

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Abstract

Physically crosslinked PVA-hydrogel microparticles are utilized for encapsulation of E. coli and M. luteus. The bacteria survive dry storage or treatment with bacteria-hostile organic solvents significantly better than unprotected bacteria as proven by culture-test experiments. The bacteria-protecting PVA microparticles are available for standard polymer-solution-processing techniques, as exemplarily shown by co-electrospinning of living bacteria encapsulated in dry PVA-hydrogel microparticles together with PVB-, PLLA-, and PCL-form organic solvents.