Publications "Derra, Sebastian"

Article in a journal

Nguyen, Lisa ; Derra, Sebastian ; Hahn, Frank:
The Relationship between Substrate Structure and Selectivity of Ketoreduction in Multimodular Polyketide Synthases : A Comparative Study of A-Type Ketoreductases from Late Modules Using Complex Precursor Analogues.
In: ACS Chemical Biology. Vol. 20 (2025) . - pp. 186-196.
ISSN 1554-8937
DOI: https://doi.org/10.1021/acschembio.4c00669

Roß-Taschner, Theresa ; Derra, Sebastian ; Stang, Jörg ; Schlotte, Luca ; Putratama, Anthony ; Hahn, Frank:
Highly Stereoselective Biocatalytic One-Pot Synthesis of Chiral Saturated Oxygen Heterocycles by Integration of a Biosynthetic Heterocyclase into Multiple-Enzyme Cascades.
In: ACS Catalysis. Vol. 14 (2024) . - pp. 13420-13428.
ISSN 2155-5435
DOI: https://doi.org/10.1021/acscatal.4c03692

Derra, Sebastian ; Hoffmann, Julia ; Hahn, Frank:
Synthesis of Biomimetic Thioesters for Studies of Ketoreductase Domains from the Biosynthesis of Cytotoxic Polyketides.
In: Synlett. Vol. 35 (2024) Issue 14 . - pp. 1707-1712.
ISSN 1437-2096
DOI: https://doi.org/10.1055/a-2216-4521

Derra, Sebastian ; Schlotte, Luca ; Hahn, Frank:
Suzuki–Miyaura Reaction in the Presence of N-Acetylcysteamine Thioesters Enables Rapid Synthesis of Biomimetic Polyketide Thioester Surrogates for Biosynthetic Studies.
In: Chemistry. Vol. 5 (2023) Issue 2 . - pp. 1407-1418.
ISSN 2624-8549
DOI: https://doi.org/10.3390/chemistry5020096

Wagner, Lisa Maria Carolin ; Stang, Jörg ; Derra, Sebastian ; Hollmann, Tim ; Hahn, Frank:
Towards understanding oxygen heterocycle-forming biocatalysts : a selectivity study of the pyran synthase PedPS7.
In: Organic & Biomolecular Chemistry. Vol. 20 (2022) Issue 48 . - pp. 9645-9649.
ISSN 1477-0539
DOI: https://doi.org/10.1039/D2OB02064E