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Silk-based materials for biomedical applications

Title data

Leal-Egaña, Aldo ; Scheibel, Thomas:
Silk-based materials for biomedical applications.
In: Biotechnology and Applied Biochemistry. Vol. 55 (March 2010) Issue 3 . - pp. 155-167.
ISSN 0885-4513
DOI: https://doi.org/10.1042/BA20090229

Official URL: Volltext

Abstract in another language

Since the beginning of civilization, humans have exploited nature as an extraordinary source of materials for medical applications. Most natural materials comprise biopolymers such as nucleic acids and protein–polysaccharides. For biomedical applications, proteins such as collagens have been traditionally employed. Other proteins are silk fibres produced by arthropods (e.g. silkworms and spiders), which provide interesting mechanical properties and the absence of toxicity. Silks present almost all characteristics desirable for biomedical applications, but the research on the underlying proteins has only recently commenced. In the present review, we summarize the current research related to silk being used as a material for cell culture and tissue engineering, particularly focusing on cell-surface adherence, mechanical and textural properties, toxicity, immunogenicity and biodegradability.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: biocompatible material; protein-based material; silk protein; tissue engineering
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 630 Agriculture
Date Deposited: 07 Jul 2015 08:58
Last Modified: 09 Apr 2018 09:09
URI: https://eref.uni-bayreuth.de/id/eprint/15980