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Thyroid hormones - From Crystal Packing to Activity to Reactivity

Title data

Schweizer, Ulrich ; Steegborn, Clemens:
Thyroid hormones - From Crystal Packing to Activity to Reactivity.
In: Angewandte Chemie International Edition. (11 September 2015) .
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.201506919

Abstract in another language

Form and substance: Through observation and careful follow-up on polymorphic forms of thyroxine (Forms I und II; black C, gray H, violet I, blue N, red O), Mondal and Mugesh have provided a stunningly simple answer to the apparent non-equivalence of thyroid hormone tablets. Their results further suggest control of deiodinase regioselectivity through the adjustment of torsional angles distant from the reactive bond.

Further data

Item Type: Article in a journal
Refereed: Yes
Additional notes: PubMed-ID: 26358899
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry > Chair Biochemistry - Univ.-Prof. Dr. Clemens Steegborn
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 17 Sep 2015 06:34
Last Modified: 17 Sep 2015 06:34
URI: https://eref.uni-bayreuth.de/id/eprint/19445