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Spider Silk: From Soluble Protein to Extraordinary Fiber

Title data

Heim, Markus ; Keerl, David ; Scheibel, Thomas:
Spider Silk: From Soluble Protein to Extraordinary Fiber.
In: Angewandte Chemie International Edition. Vol. 48 (February 2009) Issue 20 . - pp. 3584-3596.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.200803341

Official URL: Volltext

Abstract in another language

On a silky thread: Spider silks have mechanical properties that outperform most natural and synthetic fibers. Classical spinning methods have failed to mimic the highly complex natural in-vivo spinning process. Analyzing this process in combination with in-vitro findings allows the development of biomimetic spinning devices for the technical production of silk fibers (see picture).

Spider silks outrival natural and many synthetic fibers in terms of their material characteristics. In nature, the formation of a solid fiber from soluble spider silk proteins is the result of complex biochemical and physical processes that take place within specialized spinning organs. Herein, we present natural and artificial silk production processes, from gene transcription to silk protein processing and finally fiber assembly. In-vivo and in-vitro findings in the field of spider silk research are the basis for the design of new proteins and processing strategies, which will enable applications of these fascinating protein-based materials in technical and medical sciences.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: biomimetics; gene expression; protein folding; silk protein; spinning processes
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 600 Technology
Date Deposited: 22 Sep 2015 08:32
Last Modified: 26 Nov 2015 10:51
URI: https://eref.uni-bayreuth.de/id/eprint/19492