Titlebar

Export bibliographic data
Literature by the same author
plus on the publication server
plus at Google Scholar

 

Processing conditions for the formation of spider silk microspheres

Title data

Lammel, Andreas ; Schwab, Martin ; Slotta, Ute ; Winter, Gerhard ; Scheibel, Thomas:
Processing conditions for the formation of spider silk microspheres.
In: ChemSusChem. Vol. 1 (May 2008) Issue 5 . - pp. 413-416.
ISSN 1864-564X
DOI: https://doi.org/10.1002/cssc.200800030

Abstract in another language

Spider silk is a material consisting of very large (>200 kDa) proteins and has a high potential for biomedical applications as a result of its biocompatibility and biodegradability. We report on the influence of physicochemical factors on structure formation of the engineered spider silk protein eADF4(C16), which mimics the known sequence of the dragline protein ADF4 from the spider Araneus diadematus. Under certain experimental conditions, eADF4(C16) forms stable microspheres that have been analyzed with respect to sphere size, size distribution, and surface inertness upon different preparation methods (dialysis, pipette and micromixing). As a result of their material strength, biocompatibility, and the possibility of functionalization, spider silk microspheres have a high potential for the development of targeted drug-delivery systems.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 24 Sep 2015 06:49
Last Modified: 20 May 2016 06:29
URI: https://eref.uni-bayreuth.de/id/eprint/19512