Titlebar

Export bibliographic data
Literature by the same author
plus on the publication server
plus at Google Scholar

 

Structural Analysis of Spider Silk Films

Title data

Slotta, Ute ; Tammer, Michael ; Kremer, Friedrich ; Koelsch, Patrick ; Scheibel, Thomas:
Structural Analysis of Spider Silk Films.
In: Supramolecular Chemistry. Vol. 18 (2006) Issue 5 . - pp. 465-471.
ISSN 1061-0278
DOI: https://doi.org/10.1080/10610270600832042

Abstract in another language

Due to their outstanding mechanical properties, spider silks have fascinated men for a long time. Silk is composed of proteins which can not only be processed into fibers, as found in nature, but also be cast to form films in vitro. Starting with a protein solution in hexafluoroisopropanol, we were able to cast films with different properties deviated from the two spider silk proteins employed. All as-cast films revealed an α-helixrich structure and were water soluble. However, the secondary structure of One-protein films (silk films cast from one spider silk protein) could be converted from an α-helical rich to a β-sheet rich secondary structure by post-cast treatment with methanol or potassium phosphate. The structural conversion was accompanied by a higher stability as seen by water-insolubility. Depending on the employed proteins, silk films were stable in protein denaturants such as urea and guanidinium hydrochloride. Strikingly, Two-protein films (silk films cast from a mixture of both spider silk proteins) showed properties derived from both proteins, indicating that the process of film casting based on silk proteins is closely related to film casting of traditional chemical polymers. Our results reveal novel possibilities to generate protein films for applications that demand stable biocompatible polymer films.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: Araneus diadematus; Silk films; FTIR spectroscopy;
Biopolymers
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 25 Sep 2015 05:39
Last Modified: 20 May 2016 06:51
URI: https://eref.uni-bayreuth.de/id/eprint/19547