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The Impact of Exercise on Telomere Length, DNA Methylation and Metabolic Footprints

Title data

Haupt, Sandra ; Niedrist, Tobias ; Sourij, Harald ; Schwarzinger, Stephan ; Moser, Othmar:
The Impact of Exercise on Telomere Length, DNA Methylation and Metabolic Footprints.
In: Cells. Vol. 11 (January 2022) Issue 1 . - No. 153.
ISSN 2073-4409
DOI: https://doi.org/10.3390/cells11010153

Abstract in another language

Aging as a major risk factor influences the probability of developing cancer, cardiovascular disease and diabetes, amongst others. The underlying mechanisms of disease are still not fully understood, but research suggests that delaying the aging process could ameliorate these pathologies. A key biological process in aging is cellular senescence which is associated with several stressors such as telomere shortening or enhanced DNA methylation. Telomere length as well as DNA methylation levels can be used as biological age predictors which are able to detect excessive acceleration or deceleration of aging. Analytical methods examining aging are often not suitable, expensive, time-consuming or require a high level of technical expertise. Therefore, research focusses on combining analytical methods which have the potential to simultaneously analyse epigenetic, genomic as well as metabolic changes.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology
Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology > Chair Exercise Physiology - Univ.-Prof. Dr. Othmar Moser
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
Date Deposited: 18 Jan 2022 09:45
Last Modified: 18 Jan 2022 09:45
URI: https://eref.uni-bayreuth.de/id/eprint/68404