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Glycopolymer Functionalization of Engineered Spider Silk Protein-based Materials for Improved Cell Adhesion

Title data

Hardy, John G. ; Pfaff, André ; Leal-Egaña, Aldo ; Scheibel, Thomas:
Glycopolymer Functionalization of Engineered Spider Silk Protein-based Materials for Improved Cell Adhesion.
In: Macromolecular Bioscience. Vol. 14 (July 2014) Issue 7 . - pp. 936-942.
ISSN 1616-5187
DOI: https://doi.org/10.1002/mabi.201400020

Official URL: Volltext

Abstract in another language

Silk protein-based materials are promising biomaterials for application as tissue scaffolds,
due to their processability, biocompatibility, and biodegradability. The preparation of films
composed of an engineered spider silk protein (eADF4(C16)) and their functionalization with
glycopolymers are described. The glycopolymers
bind proteins found in the extracellular matrix,
providing a biomimetic coating on the films that
improves cell adhesion to the surfaces of engineered
spider silk films. Such silk-based materials
have potential as coatings for degradable implantable
devices.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: biodegradable; biomaterials; biomimetics; cell adhesion; coatings; glycopolymers
Institutions of the University: Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Faculties
Faculties > Faculty of Engineering Science > Chair Biomaterials
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 03 Mar 2015 13:22
Last Modified: 09 Apr 2018 09:07
URI: https://eref.uni-bayreuth.de/id/eprint/7736