Rephrasing anaphase : Separase FEARs shugoshin

Titelangaben

Stemmann, Olaf ; Boos, Dominik ; Gorr, Ingo H.:
Rephrasing anaphase : Separase FEARs shugoshin.
In: Chromosoma. Bd. 113 (2005) Heft 8 . - S. 409-417.
ISSN 1432-0886
DOI: https://doi.org/10.1007/s00412-005-0331-y

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Abstract

Cleavage of the ring-like cohesin complex by separase triggers segregation of sister chromatids in anaphase. This simplistic model has recently been extended by exciting discoveries on three levels: regulation of anaphase by posttranslational modifications and the cohesin protector shugoshin; non-proteolytic roles of separase; and cohesin-independent linkage of sister chromatids.