Title data
Hardy, John G. ; Leal-Egaña, Aldo ; Scheibel, Thomas:
Engineered spider silk protein-based composites for drug delivery.
In: Macromolecular Bioscience.
Vol. 13
(2013)
Issue 10
.
- pp. 1431-1437.
ISSN 1616-5195
DOI: https://doi.org/10.1002/mabi.201300233
Abstract in another language
Silk protein-based materials are promising materials for the delivery of drugs and other active ingredients, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) in combination with either a polyester (polycaprolactone) or a polyurethane (pellethane), and their physical properties are described. The release profiles are affected by both the film composition and the presence of enzymes, and release can be observed over a period of several weeks. Such silk-based composites have potential as drug eluting biocompatible coatings or implantable devices.
Further data
Item Type: | Article in a journal |
---|---|
Refereed: | Yes |
Additional notes: | Der Artikel wurde zunächst online veröffentlicht am 23.07.2013 |
Keywords: | biodegradable biomaterials; coatings; composites; drug delivery |
Institutions of the University: | Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Chair Biomaterials Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel Profile Fields > Advanced Fields > Advanced Materials Profile Fields > Advanced Fields > Molecular Biosciences Profile Fields > Advanced Fields > Polymer and Colloid Science Profile Fields > Emerging Fields > Food and Health Sciences Profile Fields Profile Fields > Advanced Fields Profile Fields > Emerging Fields |
Result of work at the UBT: | Yes |
DDC Subjects: | 600 Technology, medicine, applied sciences > 620 Engineering |
Date Deposited: | 21 Apr 2015 06:38 |
Last Modified: | 10 Oct 2023 11:21 |
URI: | https://eref.uni-bayreuth.de/id/eprint/10574 |