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Recombinant Spider Silk Proteins for Applications in Biomaterials

Title data

Spieß, Kristina ; Lammel, Andreas ; Scheibel, Thomas:
Recombinant Spider Silk Proteins for Applications in Biomaterials.
In: Macromolecular Bioscience. Vol. 10 (2010) Issue 9 . - pp. 998-1007.
ISSN 1616-5187

Official URL: Volltext

Abstract in another language

Due to their extraordinary mechanical and biochemical properties, silks have long been in focus of research. In vivo, fibers are formed from silk proteins, in vitro, however, a variety of materials can be produced in addition to fibers including capsules, particles, films, foams, and gels. The versatility of silk proteins, along with their biocompatibility, biodegradability, and potential for processing in aqueous solution under ambient conditions make silk-based materials good candidates for biomedical applications such as drug delivery systems and scaffolds for tissue engineering. Here, we summarize recent progress in research employing recombinantly produced engineered spider silk proteins with a focus on the fundamentals of silk protein processing. We highlight recombinant spider silk films and particles as morphologies that represent model systems with adjustable material properties controlled by process parameters.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: biopolymers; drug delivery systems; process parameters; recombinant spider silks; tissue engineering
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 07 Jul 2015 08:15
Last Modified: 14 Feb 2023 12:42