at Google ScholarTitle data
Leal-Egaña, Aldo ; Scheibel, Thomas:
Silk-based materials for biomedical applications.
In: Biotechnology and Applied Biochemistry.
Vol. 55
(2010)
Issue 3
.
- pp. 155-167.
ISSN 0885-4513
DOI: https://doi.org/10.1042/BA20090229
Abstract in another language
Since the beginning of civilization, humans have exploited nature as an extraordinary source of materials for medical applications. Most natural materials comprise biopolymers such as nucleic acids and protein–polysaccharides. For biomedical applications, proteins such as collagens have been traditionally employed. Other proteins are silk fibres produced by arthropods (e.g. silkworms and spiders), which provide interesting mechanical properties and the absence of toxicity. Silks present almost all characteristics desirable for biomedical applications, but the research on the underlying proteins has only recently commenced. In the present review, we summarize the current research related to silk being used as a material for cell culture and tissue engineering, particularly focusing on cell-surface adherence, mechanical and textural properties, toxicity, immunogenicity and biodegradability.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Keywords: | biocompatible material; protein-based material; silk protein; tissue engineering |
| Institutions of the University: | Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Chair Biomaterials Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel Profile Fields > Advanced Fields > Advanced Materials Profile Fields > Advanced Fields > Molecular Biosciences Profile Fields > Advanced Fields > Polymer and Colloid Science Profile Fields > Emerging Fields > Food and Health Sciences Profile Fields Profile Fields > Advanced Fields Profile Fields > Emerging Fields |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 600 Technology, medicine, applied sciences > 630 Agriculture |
| Date Deposited: | 07 Jul 2015 08:58 |
| Last Modified: | 25 Apr 2022 13:58 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/15980 |