Functional Amyloids Used by Organisms : a Lesson in Controlling Assembly

Title data

Smith, Andrew M. ; Scheibel, Thomas:
Functional Amyloids Used by Organisms : a Lesson in Controlling Assembly.
In: Macromolecular Chemistry and Physics. Vol. 211 (2010) Issue 2 . - pp. 127-135.
ISSN 1521-3935
DOI: https://doi.org/10.1002/macp.200900420

Official URL:

Abstract in another language

Amyloid has been studied primarily in relation to the disease states that it causes in humans, but in recent years, a range of proteins have been identified that self-assemble to a β-sheet rich fold as part of their native function and as such have been termed as functional amyloids.1 These functional amyloids fulfil a range of tasks within cells and extracellularly. In this paper, we will discuss the concept of functional amyloids, specifically in the sense of a structural component for the producing organism. Additionally, we will discuss how these organisms have controlled amyloid formation so that it only occurs at specific locations and at a desired time.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Keywords:	amyloid; fibres; hydrophobins; self-assembly; silk
Institutions of the University:	Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Chair Biomaterials Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel Profile Fields > Advanced Fields > Advanced Materials Profile Fields > Advanced Fields > Molecular Biosciences Profile Fields > Advanced Fields > Polymer and Colloid Science Profile Fields > Emerging Fields > Food and Health Sciences Profile Fields Profile Fields > Advanced Fields Profile Fields > Emerging Fields
Result of work at the UBT:	Yes
DDC Subjects:	600 Technology, medicine, applied sciences 600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited:	22 Sep 2015 12:04
Last Modified:	14 Feb 2023 12:36
URI:	https://eref.uni-bayreuth.de/id/eprint/19484