at Google ScholarTitle data
Lammel, Andreas ; Schwab, Martin ; Slotta, Ute ; Winter, Gerhard ; Scheibel, Thomas:
Processing conditions for the formation of spider silk microspheres.
In: ChemSusChem.
Vol. 1
(2008)
Issue 5
.
- pp. 413-416.
ISSN 1864-564X
DOI: https://doi.org/10.1002/cssc.200800030
Abstract in another language
Spider silk is a material consisting of very large (>200 kDa) proteins and has a high potential for biomedical applications as a result of its biocompatibility and biodegradability. We report on the influence of physicochemical factors on structure formation of the engineered spider silk protein eADF4(C16), which mimics the known sequence of the dragline protein ADF4 from the spider Araneus diadematus. Under certain experimental conditions, eADF4(C16) forms stable microspheres that have been analyzed with respect to sphere size, size distribution, and surface inertness upon different preparation methods (dialysis, pipette and micromixing). As a result of their material strength, biocompatibility, and the possibility of functionalization, spider silk microspheres have a high potential for the development of targeted drug-delivery systems.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Chair Biomaterials Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel Profile Fields > Advanced Fields > Advanced Materials Profile Fields > Advanced Fields > Molecular Biosciences Profile Fields > Advanced Fields > Polymer and Colloid Science Profile Fields > Emerging Fields > Food and Health Sciences Profile Fields Profile Fields > Advanced Fields Profile Fields > Emerging Fields |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 600 Technology, medicine, applied sciences 600 Technology, medicine, applied sciences > 620 Engineering |
| Date Deposited: | 24 Sep 2015 06:49 |
| Last Modified: | 14 Feb 2023 12:24 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/19512 |