Title data
Stiel, André C. ; Feldmeier, Kaspar ; Höcker, Birte:
Identification of protein scaffolds for enzyme design using scaffold selection.
In: Köhler, Valentin
(ed.):
Protein design : methods and applications. 2nd Edition. -
New York, NY
: Humana Press
,
2014
. - pp. 183-196
. - (Methods in Molecular Biology
; 1216
)
ISBN 978-1-4939-1485-2
DOI: https://doi.org/10.1007/978-1-4939-1486-9_9
Abstract in another language
The identification of suitable protein structures that can serve as scaffolds for the introduction of catalytic residues is crucial for the design of new enzymes. Here we describe how the automated and rapid scaffold search program ScaffoldSelection can be used to find the best starting points, namely protein structures that are most likely to tolerate the introduction and promote the proper formation of a specific catalytic motif.
Further data
Item Type: | Article in a book |
---|---|
Refereed: | Yes |
Institutions of the University: | Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry > Chair Biochemistry - Univ.-Prof. Dr. Birte Höcker |
Result of work at the UBT: | No |
DDC Subjects: | 500 Science 500 Science > 540 Chemistry |
Date Deposited: | 24 May 2017 06:46 |
Last Modified: | 23 Apr 2024 11:02 |
URI: | https://eref.uni-bayreuth.de/id/eprint/37238 |