Institutionen der Universität Bayreuth
Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Biochemie > Lehrstuhl Biochemie - Univ.-Prof. Dr. Birte Höcker

Sterner, Reinhard ; Höcker, Birte ; Kolmar, Harald:
Highlight issue: protein design.
In: Biological Chemistry. Bd. 398 (1 Januar 2017) Heft 1 . - S. 1-2.
DOI: 10.1515/hsz-2016-0322

Stiel, André C. ; Nellen, Mehdi ; Höcker, Birte:
PocketOptimizer and the Design of Ligand Binding Sites.
In: Stoddard, Barry L. (Hrsg.): Computational Design of Ligand Binding Proteins. - New York : Humana Press, 2016 . - S. 63-75 . - (Methods in Molecular Biology ; 1414 )
DOI: 10.1007/978-1-4939-3569-7_5

Farías-Rico, José Arcadio ; Schmidt, Steffen ; Höcker, Birte:
Evolutionary relationship of two ancient protein superfolds.
In: Nature Chemical Biology. Bd. 10 (September 2014) Heft 9 . - S. 710-715.
DOI: 10.1038/nchembio.1579

Höcker, Birte:
Design of proteins from smaller fragments : learning from evolution.
In: Current Opinion in Structural Biology. Bd. 27 (August 2014) . - S. 56-62.
DOI: 10.1016/j.sbi.2014.04.007

Scheib, Ulrike ; Shanmugaratnam, Sooruban ; Farías-Rico, José Arcadio ; Höcker, Birte:
Change in protein-ligand specificity through binding pocket grafting.
In: Journal of Structural Biology. Bd. 185 (Februar 2014) Heft 2 . - S. 186-192.
DOI: 10.1016/j.jsb.2013.06.002

Höcker, Birte ; Midelfort, Katarina:
Designing protein function : macromolecular design.
In: Journal of Structural Biology. Bd. 185 (Februar 2014) Heft 2 . - S. 135.
DOI: 10.1016/j.jsb.2014.01.011

Stiel, André C. ; Feldmeier, Kaspar ; Höcker, Birte:
Identification of protein scaffolds for enzyme design using scaffold selection.
In: Methods in Molecular Biology. Bd. 1216 (2014) . - S. 183-196.
DOI: 10.1007/978-1-4939-1486-9_9

Feldmeier, Kaspar ; Höcker, Birte:
Computational protein design of ligand binding and catalysis.
In: Current Opinion in Chemical Biology. Bd. 17 (Dezember 2013) Heft 6 . - S. 929-933.
DOI: 10.1016/j.cbpa.2013.10.002

Höcker, Birte:
Engineering chimaeric proteins from fold fragments : "hopeful monsters" in protein design.
In: Biochemical Society Transactions. Bd. 41 (Oktober 2013) Heft 5 . - S. 1137-1140.
DOI: 10.1042/BST20130099

Farías-Rico, José Arcadio ; Höcker, Birte:
Design of chimeric proteins by combination of subdomain-sized fragments.
In: Methods in Enzymology. Bd. 523 (2013) . - S. 389-405.
DOI: 10.1016/B978-0-12-394292-0.00018-7

Höcker, Birte:
Structural biology : A toolbox for protein design.
In: Nature. Bd. 491 (8 November 2012) Heft 7423 . - S. 204-205.
DOI: 10.1038/491204a

Shanmugaratnam, Sooruban ; Eisenbeis, Simone ; Höcker, Birte:
A highly stable protein chimera built from fragments of different folds.
In: Protein Engineering, Design & Selection. Bd. 25 (November 2012) Heft 11 . - S. 699-703.
DOI: 10.1093/protein/gzs074

Eisenbeis, Simone ; Proffitt, William ; Coles, Murray ; Truffault, Vincent ; Shanmugaratnam, Sooruban ; Meiler, Jens ; Höcker, Birte:
Potential of fragment recombination for rational design of proteins.
In: Journal of the American Chemical Society. Bd. 134 (7 März 2012) Heft 9 . - S. 4019-4022.
DOI: 10.1021/ja211657k

Höcker, Birte:
Protein design : A metalloenzyme reloaded.
In: Nature Chemical Biology. Bd. 8 (15 Februar 2012) Heft 3 . - S. 224-225.
DOI: 10.1038/nchembio.800

Malisi, Christoph ; Stiel, André C. ; Höcker, Birte:
Enzyme am Reißbrett.
In: BIOspektrum. Bd. 17 (2011) Heft 7 . - S. 736-738.
DOI: 10.1007/s12268-011-0117-0

Eisenbeis, Simone ; Höcker, Birte:
Evolutionary mechanism as a template for protein engineering.
In: Journal of Peptide Science. Bd. 16 (Oktober 2010) Heft 10 . - S. 538-544.
DOI: 10.1002/psc.1233

Schreier, Bettina ; Höcker, Birte:
Engineering the enolase magnesium II binding site: implications for its evolution.
In: Biochemistry. Bd. 49 (7 September 2010) Heft 35 . - S. 7582-7589.
DOI: 10.1021/bi100954f

Höcker, Birte:
Metals make proteins stick.
In: Chemistry & Biology. Bd. 17 (26 Februar 2010) Heft 2 . - S. 103-104.
DOI: 10.1016/j.chembiol.2010.02.002

Malisi, Christoph ; Kohlbacher, Oliver ; Höcker, Birte:
Automated scaffold selection for enzyme design.
In: Proteins. Bd. 77 (Oktober 2009) Heft 1 . - S. 74-83.
DOI: 10.1002/prot.22418

Höcker, Birte ; Lochner, Adriane ; Seitz, Tobias ; Claren, Jörg ; Sterner, Reinhard:
High-resolution crystal structure of an artificial (betaalpha)(8)-barrel protein designed from identical half-barrels.
In: Biochemistry. Bd. 48 (17 Februar 2009) Heft 6 . - S. 1145-1147.
DOI: 10.1021/bi802125b

Reetz, Manfred T. ; Rentzsch, Martin ; Pletsch, Andreas ; Taglieber, Andreas ; Hollmann, Frank ; Mondière, Régis J. G. ; Dickmann, Norbert ; Höcker, Birte ; Cerrone, Simona ; Haeger, Michaela C. ; Sterner, Reinhard:
A robust protein host for anchoring chelating ligands and organocatalysts.
In: ChemBioChem. Bd. 9 (3 März 2008) Heft 4 . - S. 552-564.
DOI: 10.1002/cbic.200700413

Sterner, Reinhard ; Höcker, Birte:
Catalytic versatility, stability, and evolution of the (betaalpha)8-barrel enzyme fold.
In: Chemical Reviews. Bd. 105 (November 2005) Heft 11 . - S. 4038-4055.
DOI: 10.1021/cr030191z

Höcker, Birte:
Directed evolution of (betaalpha)(8)-barrel enzymes.
In: Biomolecular Engineering. Bd. 22 (Juni 2005) Heft 1-3 . - S. 31-38.
DOI: 10.1016/j.bioeng.2004.09.005

Raasch, Carsten ; Armbrecht, Martin ; Streit, Wolfgang ; Höcker, Birte ; Sträter, Norbert ; Liebl, Wolfgang:
Identification of residues important for NAD+ binding by the Thermotoga maritima alpha-glucosidase AglA, a member of glycoside hydrolase family 4.
In: FEBS Letters. Bd. 517 (24 April 2002) Heft 1-3 . - S. 267-271.
DOI: 10.1016/S0014-5793(02)02641-8

Höcker, Birte ; Schmidt, Steffen ; Sterner, Reinhard:
A common evolutionary origin of two elementary enzyme folds.
In: FEBS Letters. Bd. 510 (16 Januar 2002) Heft 3 . - S. 133-135.
DOI: 10.1016/S0014-5793(01)03232-X

Henn-Sax, Martina ; Höcker, Birte ; Wilmanns, Matthias ; Sterner, Reinhard:
Divergent evolution of (betaalpha)8-barrel enzymes.
In: Biological Chemistry. Bd. 382 (September 2001) Heft 9 . - S. 1315-1320.
DOI: 10.1515/BC.2001.163

Höcker, Birte ; Jürgens, Catharina ; Wilmanns, Matthias ; Sterner, Reinhard:
Stability, catalytic versatility and evolution of the (betaalpha)(8)-barrel fold.
In: Current Opinion in Biotechnology. Bd. 12 (August 2001) Heft 4 . - S. 376-381.
DOI: 10.1016/S0958-1669(00)00230-5

Höcker, Birte ; Beismann-Driemeyer, Silke ; Hettwer, Stefan ; Lustig, Ariel ; Sterner, Reinhard:
Dissection of a (betaalpha)8-barrel enzyme into two folded halves.
In: Nature Structural Biology. Bd. 8 (Januar 2001) Heft 1 . - S. 32-36.
DOI: 10.1038/83021