bei Google ScholarTitelangaben
Sadeghian, Ramin Banan ; Ostrovidov, Serge ; Salehi, Sahar ; Han, Jiuhui ; Chen, Mingwei ; Khademhosseini, Ali:
An electrochemical biosensor based on gold microspheres and nanoporous gold for real-time detection of superoxide anion in skeletal muscle tissue.
In:
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). -
Piscataway, NJ
: IEEE
,
2015
. - S. 7962-7965
ISBN 978-1-4244-9271-8
DOI: https://doi.org/10.1109/EMBC.2015.7320239
Abstract
Superoxide anion (SOA) as a member of reactive oxygen species (ROS) group is involved in various physiological and pathological states. For instance, generation of SOA is known to increase with skeletal muscle contractile activity and fatigue. It is therefore important to selectively detect and accurately quantify the release of SOA within both physiological and pathological levels. We report fabrication and characterization of a cytochrome-c functionalized SOA biosensor built on commercially available miniaturized screen-printed electrodes made of gold microspheres. The device was first tested and calibrated in a xanthine/xanthine oxidase (XOD) system and then employed to detect SOA release from C2C12 myoblasts and myotubes upon stimulation with PMA.
Weitere Angaben
| Publikationsform: | Aufsatz in einem Buch |
|---|---|
| Begutachteter Beitrag: | Ja |
| Institutionen der Universität: | Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Biomaterialien |
| Titel an der UBT entstanden: | Nein |
| Themengebiete aus DDC: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit 600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften |
| Eingestellt am: | 10 Mär 2023 11:05 |
| Letzte Änderung: | 10 Mär 2023 11:05 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/74186 |