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Electrospun nanofibrous scaffolds and corneal tissue engineering

Titelangaben

Salehi, Sahar ; Bahners, T. ; Gutmann, J. ; Fuchsluger, T.:
Electrospun nanofibrous scaffolds and corneal tissue engineering.
In: Acta Ophthalmologica. Bd. 92 (2014) Heft s253 .
ISSN 1755-3768
DOI: https://doi.org/10.1111/j.1755-3768.2014.4631.x

Abstract

Generation of a tissue-engineered cornea composed of biomaterials and cells will reduce dependency on the short supply of donor corneal tissue. In the last decade, the supply of viable donor tissue for corneal transplants is relatively less than the demand for donor corneal tissue. A tissue- engineered cornea that incorporates cells with a biocompatible and aligned nanofibrous scaffolds that replicates the stromal extracellular matrix will be an optimal alternative to synthetic replacements and donor tissue. Biodegradable aligned electrospun substitutes of a tissue- engineered cornea would also serve as an in- vivo and ex-vivo platform for investigating the mechanisms of corneal diseases, regeneration of corneal cell layers and human cellular responses to new ophthalmic drugs.

Weitere Angaben

Publikationsform: Artikel in einer Zeitschrift
Begutachteter Beitrag: Ja
Institutionen der Universität: Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Biomaterialien
Titel an der UBT entstanden: Nein
Themengebiete aus DDC: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften
Eingestellt am: 13 Mär 2023 10:17
Letzte Änderung: 13 Mär 2023 10:17
URI: https://eref.uni-bayreuth.de/id/eprint/74207