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Electrospun nanofibrous scaffolds and corneal tissue engineering

Title data

Salehi, Sahar ; Bahners, T. ; Gutmann, J. ; Fuchsluger, T.:
Electrospun nanofibrous scaffolds and corneal tissue engineering.
In: Acta Ophthalmologica. Vol. 92 (2014) Issue s253 .
ISSN 1755-3768
DOI: https://doi.org/10.1111/j.1755-3768.2014.4631.x

Abstract in another language

Generation of a tissue-engineered cornea composed of biomaterials and cells will reduce dependency on the short supply of donor corneal tissue. In the last decade, the supply of viable donor tissue for corneal transplants is relatively less than the demand for donor corneal tissue. A tissue- engineered cornea that incorporates cells with a biocompatible and aligned nanofibrous scaffolds that replicates the stromal extracellular matrix will be an optimal alternative to synthetic replacements and donor tissue. Biodegradable aligned electrospun substitutes of a tissue- engineered cornea would also serve as an in- vivo and ex-vivo platform for investigating the mechanisms of corneal diseases, regeneration of corneal cell layers and human cellular responses to new ophthalmic drugs.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Engineering Science > Chair Biomaterials
Result of work at the UBT: No
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 13 Mar 2023 10:17
Last Modified: 13 Mar 2023 10:17
URI: https://eref.uni-bayreuth.de/id/eprint/74207