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Glycopolymer Functionalization of Engineered Spider Silk Protein-based Materials for Improved Cell Adhesion

Title data

Hardy, John G. ; Pfaff, André ; Leal-Egaña, Aldo ; Scheibel, Thomas:
Glycopolymer Functionalization of Engineered Spider Silk Protein-based Materials for Improved Cell Adhesion.
In: Macromolecular Bioscience. Vol. 14 (2014) Issue 7 . - pp. 936-942.
ISSN 1616-5195
DOI: https://doi.org/10.1002/mabi.201400020

Official URL: Volltext

Abstract in another language

Silk protein-based materials are promising biomaterials for application as tissue scaffolds, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) and their functionalization with glycopolymers are described. The glycopolymers bind proteins found in the extracellular matrix, providing a biomimetic coating on the films that improves cell adhesion to the surfaces of engineered spider silk films. Such silk-based materials have potential as coatings for degradable implantable devices.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: biodegradable; biomaterials; biomimetics; cell adhesion; coatings; glycopolymers
Institutions of the University: Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Faculties
Faculties > Faculty of Engineering Science > Chair Biomaterials
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 03 Mar 2015 13:22
Last Modified: 10 Oct 2023 11:20
URI: https://eref.uni-bayreuth.de/id/eprint/7736