Titelangaben
Medda, Rebecca ; Giske, Arnold ; Cavalcanti-Adam, Elisabetta Ada:
Challenges in imaging cell surface receptor clusters.
In: Optics and Lasers in Engineering.
Bd. 76
(2016)
.
- S. 3-8.
ISSN 1873-0302
DOI: https://doi.org/10.1016/j.optlaseng.2015.03.020
Abstract
Super-resolution microscopy offers unique tools for visualizing and resolving cellular structures at the molecular level. STED microscopy is a purely optical method where neither complex sample preparation nor mathematical post-processing is required. Here we present the use of STED microscopy for imaging receptor cluster composition. We use two-color STED to further determine the distribution of two different receptor subunits of the family of receptor serine/threonine kinases in the presence or absence of their ligands. The implications of receptor clustering on the downstream signaling are discussed, and future challenges are also presented.
Weitere Angaben
Publikationsform: | Artikel in einer Zeitschrift |
---|---|
Begutachteter Beitrag: | Ja |
Keywords: | BMP receptors; STED microscopy; Super-resolution microscopy; Fluorescence microscopy |
Institutionen der Universität: | Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Zelluläre Biomechanik > Lehrstuhl Zelluläre Biomechanik - Univ.-Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam |
Titel an der UBT entstanden: | Nein |
Themengebiete aus DDC: | 600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften |
Eingestellt am: | 12 Jun 2023 11:32 |
Letzte Änderung: | 12 Jun 2023 11:32 |
URI: | https://eref.uni-bayreuth.de/id/eprint/81180 |