at Google ScholarTitle data
Medda, Rebecca ; Giske, Arnold ; Cavalcanti-Adam, Elisabetta Ada:
Challenges in imaging cell surface receptor clusters.
In: Optics and Lasers in Engineering.
Vol. 76
(2016)
.
- pp. 3-8.
ISSN 1873-0302
DOI: https://doi.org/10.1016/j.optlaseng.2015.03.020
Abstract in another language
Super-resolution microscopy offers unique tools for visualizing and resolving cellular structures at the molecular level. STED microscopy is a purely optical method where neither complex sample preparation nor mathematical post-processing is required. Here we present the use of STED microscopy for imaging receptor cluster composition. We use two-color STED to further determine the distribution of two different receptor subunits of the family of receptor serine/threonine kinases in the presence or absence of their ligands. The implications of receptor clustering on the downstream signaling are discussed, and future challenges are also presented.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Keywords: | BMP receptors; STED microscopy; Super-resolution microscopy; Fluorescence microscopy |
| Institutions of the University: | Faculties > Faculty of Engineering Science > Chair Cellular Biomechanics > Chair Cellular Biomechanics - Univ.-Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam |
| Result of work at the UBT: | No |
| DDC Subjects: | 600 Technology, medicine, applied sciences > 620 Engineering |
| Date Deposited: | 12 Jun 2023 11:32 |
| Last Modified: | 12 Jun 2023 11:32 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/81180 |