at Google ScholarTitle data
Stemmann, Olaf ; Boos, Dominik ; Gorr, Ingo H.:
Anaphase Topsy-Turvy : Cdk1 a securin, separase a CKI.
In: Cell Cycle.
Vol. 5
(2006)
Issue 1
.
- pp. 11-13.
ISSN 1551-4005
DOI: https://doi.org/10.4161/cc.5.1.2296
Abstract in another language
Chromosome segregation in mitosis and meiosis is triggered by activation of a large protease, separase. While it has been known for some time that the anaphase inhibitor securin regulates separase activity recent work shows that this is only half the story. In vertebrates Cdk1-dependent inhibition of separase represents a second, securin-independent branch of anaphase regulation. Furthermore, an unanticipated ability of separase to inhibit Cdk1 suggests additional, nonproteolytic functions of separase.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics > Chair Genetics - Univ.-Prof. Dr. Olaf Stemmann Profile Fields > Advanced Fields > Molecular Biosciences Research Institutions > Central research institutes > Bayreuth Center for Molecular Biosciences - BZMB Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics Profile Fields Profile Fields > Advanced Fields Research Institutions Research Institutions > Central research institutes |
| Result of work at the UBT: | No |
| DDC Subjects: | 500 Science > 570 Life sciences, biology |
| Date Deposited: | 27 Mar 2015 07:16 |
| Last Modified: | 06 Sep 2023 12:56 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/8552 |