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Walking by design: how to build artificial molecular motors made of proteins

Titelangaben

Nilsson, Patrik Felix ; Zink, Anna ; Laprévote, Olivier ; Korosec, Chapin S. ; Gustafsson, Nils ; Robertson, Neil O. ; Forde, Nancy ; Eichhorn, Ralf ; Höcker, Birte ; Curmi, Paul ; Linke, Heiner:
Walking by design: how to build artificial molecular motors made of proteins.
Bayreuth , 2024
DOI: https://doi.org/10.1088/2399-1984/ad7d7e

Abstract

To design an artificial protein-based molecular motor that can autonomously step along a track is a key challenge of protein design and synthetic biology. We lay out a roadmap for how to achieve this aim, based on a modular approach that combines the use of natural, non-motor proteins with de novo design. We define what can be considered to constitute a successful artificial protein motor, identify key steps along the path to achieve these designs, and provide a vision for the future beyond this aim.

Weitere Angaben

Publikationsform: Preprint, Postprint
Institutionen der Universität: Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Biochemie III - Proteindesign > Lehrstuhl Biochemie III - Proteindesign - Univ.-Prof. Dr. Birte Höcker
Titel an der UBT entstanden: Ja
Themengebiete aus DDC: 500 Naturwissenschaften und Mathematik > 540 Chemie
Eingestellt am: 26 Sep 2024 05:32
Letzte Änderung: 26 Sep 2024 06:51
URI: https://eref.uni-bayreuth.de/id/eprint/90482