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Robust β‐Sheet Peptide Reinforced Polymer Fibers

Title data

Chan, Nicholas J. ; Lentz, Sarah ; Gurr, Paul A. ; Tan, Shereen ; Schultebeyring, Mona ; Rosenfeldt, Sabine ; Schenk, Anna ; Scheibel, Thomas ; Qiao, Greg G.:
Robust β‐Sheet Peptide Reinforced Polymer Fibers.
In: Small Science. (2025) . - 2500115.
ISSN 2688-4046
DOI: https://doi.org/10.1002/smsc.202500115

Abstract in another language

In natural silks, β-sheet crystals are embedded within an amorphous matrix resulting in polypeptide-based nanocomposites. These β-sheet crystals contribute to the subsequent high strength and toughness of spider silk. Consequently, imitation and mimicry of such concepts utilizing polypeptides provide a pathway toward putatively achieving similar properties. Herein, the introduction of poly(l-valine) (PVal) β-sheet nanocrystals into different fibers is investigated. Analysis of micro- and nanoscale features shows that polyvaline β-sheets could be implemented into fibers made from different polymer classes, ranging from standard polymers (polycaprolactone (PCL), Nylon 6) to biopolymers like cellulose and recombinant spider silk. The in situ implementation of PVal during wet-spinning leads to a significant change in the resulting mechanical properties, depending on the polymer used.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry IV - Bioinspirierte Kolloidsysteme und Streumethoden
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry IV - Bioinspirierte Kolloidsysteme und Streumethoden > Chair Physical Chemistry IV - Bioinspirierte Kolloidsysteme und Streumethoden - Univ.-Prof. Dr. Anna Schenk
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Polymer and Colloid Science
Research Institutions > Affiliated Institutes > Bavarian Polymer Institute (BPI)
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 04 Jun 2025 05:39
Last Modified: 04 Jun 2025 05:39
URI: https://eref.uni-bayreuth.de/id/eprint/93884