Microplastics, Skin Disease, and Dermatology : Evidence and Perspectives

Titelangaben

Niebel, Dennis ; Saha, Susanne ; Kunz, Werner ; Evers, Beatrix ; Löder, Martin G. J. ; Ramsperger, Anja ; Laforsch, Christian:
Microplastics, Skin Disease, and Dermatology : Evidence and Perspectives.
In: Dermatologic Clinics. (14 Oktober 2025) .
ISSN 1558-0520
DOI: https://doi.org/10.1016/j.det.2025.08.001

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Abstract

Microplastics (MPs) and nanoplastics (NPs), combined referred to as MNPs, are ubiquitously reported in aquatic and terrestrial ecosystems, as well as in the atmosphere and indoor air. Hence, MNPs are in daily contact with barrier organs including the skin and mucous membranes. The polymeric structure of plastics and the chemicals used, such as additives or catalysts, as well as residual monomers, bear the potential to exert various physical, chemical, and biologic effects on the integumentary system. Some NP particles may transpass the epidermis and enter the circulation via lymphatic or venous drainage, eventually accumulating in other organs as well. This article aims to equip clinical dermatologists with a comprehensive overview on MNPs, including a summary of available data on potential negative effects on skin health. Importantly, plastic production and MNPs are bidirectionally intertwined with climate change, another threat to skin health and the focus of this themed issue. Ultimately, we encourage the dermatologic community to explore MNPs and their potential implications for patient care. To support this, we provide fundamental insights into laboratory investigations focusing on MNP detection.