Titlebar

Export bibliographic data
Literature by the same author
plus on the publication server
plus at Google Scholar

 

Machine learning predictive model for severe COVID-19

Title data

Kang, Jianhong ; Chen, Ting ; Luo, Honghe ; Luo, Yifeng ; Du, Guipeng ; Yang, Mia Jiming:
Machine learning predictive model for severe COVID-19.
In: Infection, Genetics and Evolution. Vol. 90 (28 January 2021) .
ISSN 1567-1348
DOI: https://doi.org/10.1016/j.meegid.2021.104737

Project information

Project financing: Andere

Abstract in another language

To develop a modified predictive model for severe COVID-19 in people infected with Sars-Cov-2. We developed the predictive model for severe patients of COVID-19 based on the clinical date from the Tumor Center of Union Hospital affiliated with Tongji Medical College, China. A total of 151 cases from Jan. 26 to Mar. 20, 2020, were included. Then we followed 5 steps to predict and evaluate the model: data preprocessing, data splitting, feature selection, model building, prevention of overfitting, and Evaluation, and combined with artificial neural network algorithms. We processed the results in the 5 steps. In feature selection, ALB showed a strong negative correlation (r = 0.771, P < 0.001) whereas GLB (r = 0.661, P < 0.001) and BUN (r = 0.714, P < 0.001) showed a strong positive correlation with severity of COVID-19. TensorFlow was subsequently applied to develop a neural network model. The model achieved good prediction performance, with an area under the curve value of 0.953(0.889–0.982). Our results showed its outstanding performance in prediction. GLB and BUN may be two risk factors for severe COVID-19. Our findings could be of great benefit in the future treatment of patients with COVID-19 and will help to improve the quality of care in the long term. This model has great significance to rationalize early clinical interventions and improve the cure rate.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: Severe COVID-19; Machine learning; Predictive model
Institutions of the University: Faculties > Faculty of Law, Business and Economics > Chair Healthcare Management and Health Sciences
Faculties > Faculty of Law, Business and Economics > Chair Healthcare Management and Health Sciences > Chair Healthcare Management and Health Sciences - Univ.-Prof. Dr. Dr. Dr. h.c. Eckhard Nagel
Result of work at the UBT: No
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
Date Deposited: 09 Mar 2021 06:38
Last Modified: 09 Mar 2021 06:38
URI: https://eref.uni-bayreuth.de/id/eprint/63732