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Doblhofer, Elena ; Heidebrecht, Aniela ; Scheibel, Thomas:
To spin or not to spin: spider silk fibers and more.
In: Applied Microbiology and Biotechnology.
Bd. 99
(2015)
Heft 19
.
- S. 9361-9380.
ISSN 1432-0614
DOI: https://doi.org/10.1007/s00253-015-6948-8
Abstract
Spider silk fibers have a sophisticated hierarchical structure composed of proteins with highly repetitive sequences. Their extraordinary mechanical properties, defined by a unique combination of strength and extensibility, are superior to most man-made fibers. Therefore, spider silk has fascinated mankind for thousands of years. However, due to their aggressive territorial behavior, farming of spiders is not feasible on a large scale. For this reason, biotechnological approaches were recently developed for the production of recombinant spider silk proteins. These recombinant proteins can be assembled into a variety of morphologies with a great range of properties for technical and medical applications. Here, the different approaches of biotechnological production and the advances in material processing toward various applications will be reviewed