Engineered Microcapsules Fabricated from Reconstituted Spider Silk

Titelangaben

Hermanson, Kevin D. ; Hümmerich, Daniel ; Scheibel, Thomas ; Bausch, Andreas R.:
Engineered Microcapsules Fabricated from Reconstituted Spider Silk.
In: Advanced Materials. Bd. 19 (2007) Heft 14 . - S. 1810-1815.
ISSN 1521-4095
DOI: https://doi.org/10.1002/adma.200602709

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Abstract

Recombinant spider-silk proteins are used to produce responsive microcapsules with good mechanical and chemical stability (see figure). Emulsion interfaces are harnessed to induce the controlled self-assembly of these proteins into predominantly β-sheet configurations, resulting in a mechanically stable thin polymer shell. Capsules transferred into a continuous phase can readily encapsulate large molecules, while allowing small molecules to permeate freely.