Veröffentlichungen "Shanmugaratnam, Sooruban"

2024

Kröger, Pascal ; Stiel, Andre C. ; Stüven, Birthe ; Shanmugaratnam, Sooruban ; Schoch, Susanne ; Wachten, Dagmar ; Höcker, Birte:
A fluorescent biosensor for the visualization of agmatine.
Bayreuth , 2024
DOI: https://doi.org/10.1101/2024.07.27.605435

Beck, Julian ; Shanmugaratnam, Sooruban ; Höcker, Birte:
Diversifying de novo TIM barrels by hallucination.
In: Protein Science. Bd. 33 (2024) Heft 6 . - e5001.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.5001

Toledo‐Patiño, Saacnicteh ; Goetz, Sara Kathrin ; Shanmugaratnam, Sooruban ; Höcker, Birte ; Farías‐Rico, José Arcadio:
Molecular handcraft of a well‐folded protein chimera.
In: FEBS Letters. Bd. 598 (2024) Heft 11 . - S. 1375-1386.
ISSN 1873-3468
DOI: https://doi.org/10.1002/1873-3468.14856

2023

Kordes, Sina ; Beck, Julian ; Shanmugaratnam, Sooruban ; Flecks, Merle ; Höcker, Birte:
Physics-based approach to extend a de novo TIM barrel with rationally designed helix-loop-helix motifs.
In: Protein Engineering, Design & Selection. Bd. 36 (2023) . - gzad012.
ISSN 1741-0134
DOI: https://doi.org/10.1093/protein/gzad012

Michel, Florian ; Shanmugaratnam, Sooruban ; Romero-Romero, Sergio ; Höcker, Birte:
Structures of permuted halves of a modern ribose-binding protein.
In: Acta Crystallographica Section D Structural Biology. Bd. 79 (2023) . - S. 40-49.
ISSN 2059-7983
DOI: https://doi.org/10.1107/S205979832201186X

2022

Rhys, Guto G. ; Cross, Jessica A. ; Dawson, William M. ; Thompson, Harry F. ; Shanmugaratnam, Sooruban ; Savery, Nigel J. ; Dodding, Mark P. ; Höcker, Birte ; Woolfson, Derek N.:
De novo designed peptides for cellular delivery and subcellular localisation.
In: Nature Chemical Biology. Bd. 18 (2022) Heft 9 . - S. 999-1004.
ISSN 1552-4469
DOI: https://doi.org/10.1038/s41589-022-01076-6

2021

Herud-Sikimić, Ole ; Stiel, André C. ; Kolb, Martina ; Shanmugaratnam, Sooruban ; Berendzen, Kenneth W. ; Feldhaus, Christian ; Höcker, Birte ; Jürgens, Gerd:
A biosensor for the direct visualization of auxin.
In: Nature. Bd. 592 (2021) Heft 7856 . - S. 768-772.
ISSN 1476-4687
DOI: https://doi.org/10.1038/s41586-021-03425-2

Kröger, Pascal ; Shanmugaratnam, Sooruban ; Ferruz, Noelia ; Schweimer, Kristian ; Höcker, Birte:
A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
In: Structure. Bd. 29 (2021) Heft 5 . - S. 433-443.
ISSN 0969-2126
DOI: https://doi.org/10.1016/j.str.2020.12.005

Wiese, Jonas Gregor ; Shanmugaratnam, Sooruban ; Höcker, Birte:
Extension of a de novo TIM barrel with a rationally designed secondary structure element.
In: Protein Science. Bd. 30 (2021) Heft 5 . - S. 982-989.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.4064

Kröger, Pascal ; Shanmugaratnam, Sooruban ; Scheib, Ulrike ; Höcker, Birte:
Fine-tuning spermidine binding modes in the putrescine binding protein PotF.
In: The Journal of Biological Chemistry. Bd. 297 (2021) Heft 6 . - 101419.
ISSN 1083-351X
DOI: https://doi.org/10.1016/j.jbc.2021.101419

Romero-Romero, Sergio ; Costas, Miguel ; Silva Manzano, Daniel-Adriano ; Kordes, Sina ; Rojas-Ortega, Erendira ; Tapia, Cinthya ; Guerra, Yasel ; Shanmugaratnam, Sooruban ; Rodríguez-Romero, Adela ; Baker, David ; Höcker, Birte ; Fernández-Velasco, D. Alejandro:
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
In: Journal of Molecular Biology. Bd. 433 (2021) Heft 18 . - 167153.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2021.167153

2018

Banda-Vázquez, Jesús ; Shanmugaratnam, Sooruban ; Rodríguez-Sotres, Rogelio ; Torres-Larios, Alfredo ; Höcker, Birte ; Sosa-Peinado, Alejandro:
Redesign of LAOBP to bind novel l-amino acid ligands.
In: Protein Science. Bd. 27 (2018) Heft 5 . - S. 957-968.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.3403

2014

Scheib, Ulrike ; Shanmugaratnam, Sooruban ; Farías-Rico, José Arcadio ; Höcker, Birte:
Change in protein-ligand specificity through binding pocket grafting.
In: Journal of Structural Biology. Bd. 185 (2014) Heft 2 . - S. 186-192.
ISSN 1047-8477
DOI: https://doi.org/10.1016/j.jsb.2013.06.002

2012

Shanmugaratnam, Sooruban ; Eisenbeis, Simone ; Höcker, Birte:
A highly stable protein chimera built from fragments of different folds.
In: Protein Engineering, Design & Selection. Bd. 25 (2012) Heft 11 . - S. 699-703.
ISSN 1741-0134
DOI: https://doi.org/10.1093/protein/gzs074

Eisenbeis, Simone ; Proffitt, William ; Coles, Murray ; Truffault, Vincent ; Shanmugaratnam, Sooruban ; Meiler, Jens ; Höcker, Birte:
Potential of fragment recombination for rational design of proteins.
In: Journal of the American Chemical Society. Bd. 134 (2012) Heft 9 . - S. 4019-4022.
ISSN 1520-5126
DOI: https://doi.org/10.1021/ja211657k